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    ISTDP new research

    Feeling Is the Cure: How Emotional Breakthroughs Drive Change in ISTDP for GAD

    • Category
      Pilot Study
    • Research
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    Research Title

    ISTDP for generalized anxiety disorder: A pilot effectiveness and process-outcome study.

    CATEGORIES
    • Anxiety
    • Generalized Anxiety
    • Social Anxiety
    RESEARCH KEYWORDS
    • anxiety
    • cost-effectivenes
    • emotion processing
    • general anxiety disorder
    Author(s)
    Peter Lilliengren; Robert Johansson; Joel M. Town; Steve Kisely; Allan Abbass
    ABSTRACT

    The objective was to evaluate the clinical- and cost-effectiveness of ISTDP for GAD and to examine whether in-treatment mobilization of unprocessed complex emotions (MUCE) predicted outcome. In a naturalistic sample of 215 adults, an average of 8.3 ISTDP sessions produced significant symptom and interpersonal improvements, sustained healthcare cost reductions over 4 years, and higher MUCE levels were associated with larger treatment gains. ​Lilliengren_et_al_2017_…

    RESEARCH DETAILS
    • (N)umber of Participants
      215
    • Number Of Sessions
      8
    • Age Group
      Adults
    • Control Group
      None
    RESEARCH INFO
    • Research Design
      Pilot Study
    • Interventions
      ISTDP
    • Publication Year
      2017
    • Journal / Affiliation / Conference
      Clinical Psychology & Psychotherapy (Wiley), 2017
    • DOI / Link To Paper
      https://doi.org/10.1002/cpp.2101
    CLINICAL APPLICATION AND LEARNING POINTS

    Clinical Applications and Learning Points for ISTDP Therapists

    This pilot study provides important insights into the clinical effectiveness and mechanisms of change when using Intensive Short-Term Dynamic Psychotherapy (ISTDP) with patients diagnosed with Generalized Anxiety Disorder (GAD). Based on a large, naturalistic outpatient sample (N = 215), the study shows that ISTDP can meaningfully reduce psychiatric symptoms and interpersonal problems while also leading to substantial and sustained reductions in healthcare costs—up to four years post-treatment.

    A central finding is the correlation between improved outcomes and the degree of mobilization of unprocessed complex emotions (MUCE) during treatment. This adds compelling evidence to the ISTDP theory that it is not just the technique, but the emotional depth reached in session—especially when linked to attachment trauma—that drives therapeutic change.

    Key Clinical Implications:

    • ISTDP is effective for GAD, even in a comorbid, real-world population. Despite the chronic nature of GAD, the average patient received only 8.3 sessions (including a trial therapy), with significant pre-to-post treatment improvement in both symptoms and interpersonal functioning.
    • Cost-effectiveness is clinically relevant. Healthcare use dropped year by year, with physician and hospital costs falling below population norms within 2–4 years post-treatment. This suggests ISTDP may be both clinically impactful and financially sustainable for healthcare systems.
    • Emotional experiencing is not optional—it’s central. The level of MUCE achieved during treatment was significantly associated with greater symptom and relational improvements. In other words, therapists who successfully support patients in feeling through repressed grief, guilt, rage, and longing see stronger outcomes.
    • “Partial Breakthrough” is often achievable and beneficial. While many patients in the study reached only a moderate level of emotional access (MUCE level ~3), this still led to meaningful gains. However, deeper breakthroughs—where patients experience full complex emotions with direct links to attachment trauma—were associated with even better results.
    • GAD symptoms (like worry and rumination) may function as defenses. In ISTDP, these are not treated as cognitive distortions to be challenged, but rather as automatic defenses that serve to avoid painful emotions. Clarifying and confronting these defenses is an essential part of the therapeutic strategy.
    • Trial therapy can be potent—even when it’s the only session. Roughly one-third of patients only received the extended initial interview, often due to geographic limitations. Yet this session alone sometimes yielded measurable benefit, especially when MUCE was mobilized. This supports the power of a focused, emotionally engaging initial intervention.
    • Therapist training and supervision matter. Treatments were delivered by 38 therapists with varying levels of ISTDP training. Regular video-based supervision ensured model fidelity, showing that ISTDP can be delivered effectively by trainees under experienced guidance.

    Learning Points for Practitioners:

    • Focus on emotional breakthrough, not just interpretation. Therapists should prioritize interventions that increase emotional experiencing over intellectual insight alone.
    • Work toward activating the unconscious therapeutic alliance (UTA). Pay attention to signals of rising emotional closeness, anxiety, and resistance—these mark key turning points for processing attachment-related conflict.
    • Use the MUCE scale conceptually. Even without formal ratings, therapists can monitor how deeply the patient is engaging emotionally and whether core feelings (grief, rage, guilt, love) are becoming accessible.
    • Don’t underestimate single-session work. Trial therapy may serve not just as an assessment tool, but as a meaningful intervention in its own right—especially in systems where long-term therapy isn’t feasible.
    • Match treatment format to patient readiness. For fragile patients, the graded format of ISTDP should be used. For those with higher defenses but greater tolerance, the standard format is appropriate.

    Conclusion

    This study supports the use of ISTDP as an efficient, cost-reducing, and emotionally transformative treatment for GAD, particularly when therapists can help patients access the complex feelings linked to early relational trauma. It affirms that emotional depth—not duration—is the key therapeutic ingredient, and that helping patients feel more fully may do more than reduce symptoms—it can shift their entire trajectory of health and functioning.

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