The objective was to evaluate the clinical- and cost-effectiveness of ISTDP for GAD and to examine whether in-treatment mobilization of unprocessed complex emotions (MUCE) predicted outcome. In a naturalistic sample of 215 adults, an average of 8.3 ISTDP sessions produced significant symptom and interpersonal improvements, sustained healthcare cost reductions over 4 years, and higher MUCE levels were associated with larger treatment gains. Lilliengren_et_al_2017_…
This pilot study provides important insights into the clinical effectiveness and mechanisms of change when using Intensive Short-Term Dynamic Psychotherapy (ISTDP) with patients diagnosed with Generalized Anxiety Disorder (GAD). Based on a large, naturalistic outpatient sample (N = 215), the study shows that ISTDP can meaningfully reduce psychiatric symptoms and interpersonal problems while also leading to substantial and sustained reductions in healthcare costs—up to four years post-treatment.
A central finding is the correlation between improved outcomes and the degree of mobilization of unprocessed complex emotions (MUCE) during treatment. This adds compelling evidence to the ISTDP theory that it is not just the technique, but the emotional depth reached in session—especially when linked to attachment trauma—that drives therapeutic change.
This study supports the use of ISTDP as an efficient, cost-reducing, and emotionally transformative treatment for GAD, particularly when therapists can help patients access the complex feelings linked to early relational trauma. It affirms that emotional depth—not duration—is the key therapeutic ingredient, and that helping patients feel more fully may do more than reduce symptoms—it can shift their entire trajectory of health and functioning.
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